GlpBio

NG 52

目录号: GC36732纯度: >99.50%同义词: 2-[[6-[(3-氯苯基)氨基]-9-异丙基-9H-嘌呤-2-基]氨基]乙醇,Compound 52
An inhibitor of yeast cyclin-dependent kinases
NG 52
Cas No.: 212779-48-1
规格价格库存数量操作
5mg¥1,306.00现货
1
10mg¥2,344.00现货
1
50mg¥7,072.00现货
1
100mg¥9,207.00现货
1
200mg询价现货
1
500mg询价现货
1
10mM (in 1mL DMSO)¥1,436.00现货
1
Free Sample (0.1-0.5 mg)询价现货
1
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文献被引

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    183(7):1867-1883 (2020)
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产品描述 Description

NG 52 is a tri-substituted purine that binds to the ATP-binding site of yeast cyclin-dependent kinases, inhibiting Cdc28p and Pho85p (IC50s = 7 and 2 ?M, respectively).1 It is ineffective against the yeast kinases Kin28p, Srb10, and Cak1p. NG 52 is cell permeable and inhibits the growth of S. cerevisiae (GI50 = 30 ?M).1 It is an analog of purvalanol A , a potent inhibitor of mammalian cyclin-dependent kinases.1

1.Gray, N.S., Wodicka, L., Thunnissen, A.M.W.H., et al.Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitorsScience281(5376)533-538(1998)

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
212779-48-1
同义词
2-[[6-[(3-氯苯基)氨基]-9-异丙基-9H-嘌呤-2-基]氨基]乙醇,Compound 52
SMILES
ClC1=CC(NC2=NC(NCCO)=NC3=C2N=CN3C(C)C)=CC=C1
分子式
C16H19ClN6O
分子量
346.81 g/mol
溶解性
DMSO: 100 mg/mL (288.34 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol