Glycerol

Animal experiment:

Rats: Experimental acute renal failure was induced in male Wistar rats 230-300 g by an injection of glycerol dissolved in saline (50% v/v, 10 mL/kg) into the leg muscle after a 24-h period of water deprivation[3].

References:

[1]. Pennings S, et al. Effect of glycerol on the separation of nucleosomes and bent DNA in low ionic strengthpolyacrylamide gel electrophoresis. Nucleic Acids Res. 1992 Dec 25;20(24):6667-72.
[2]. Yazdani SS, et al. Anaerobic fermentation of glycerol: a path to economic viability for the biofuelsindustry. Curr Opin Biotechnol. 2007 Jun;18(3):213-9.
[3]. Huang ZH, et al. Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure. Eur J Pharmacol. 2000 Oct 20;406(3):453-60.