Fluconazole mesylate

Fluconazole is a triazole antifungal agent that is effective against most Candida strains.¹ In vivo fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, and histoplasmosis.²

1.Herbrecht, R., Nivoix, Y., Fohrer, C., et al.Management of systemic fungal infections: Alternatives to itraconazoleJ. Antimicrob. Chemother.56(Suppl 1)i39-i48(2005) 2.Saag, M.S., and Dismukes, W.E.Azole antifungal agents: Emphasis on new triazolesAntimicrob. Agents Chemother.32(1)1-8(1988)