Glucose 6-Phosphate is glucose produced by phosphorylation of glucose (on the hydroxyl group of carbon 6) [1]. D-Glucose 6-Phosphate is a common molecule in cells, most glucose entering cells is phosphorylated in this way, and it is located at the starting point of two major metabolic pathways: glycolysis and the pentose phosphate pathway [2]. D-Glucose 6-Phosphate can also be converted into glycogen or starch and stored in cells [3]. D-Glucose 6-Phosphate can be used as a substrate to measure recombinant mannitol-1-phosphatase (M1Pase) activity[4]. This product is in the form of an aqueous solution with a concentration of 1 M (260 mg/ml).
References:
[1]Olsen B B, Gjedde A, Vilstrup M H, et al. Linked hexokinase and glucose-6-phosphatase activities reflect grade of ovarian malignancy[J]. Molecular Imaging and Biology, 2019, 21: 375-381.
[2]Litwack, Gerald .Chapter 6-Insulin and Sugars.Human Biochemistry. Academic Press.2018:131-160.
[3]Lal M A. Metabolism of storage carbohydrates[J]. Plant physiology, development and metabolism. Springer Nature, Singapore. Doi, 2018, 10: 978-981.
[4] Groisillier A, Tonon T. Determination of Recombinant Mannitol-1-phosphatase Activity from Ectocarpus sp[J]. Bio-protocol, 2016, 6(16): e1896-e1896.
D-Glucose 6-Phosphate是葡萄糖经过磷酸化(在第6号碳的羟基上)生成的葡萄糖[1]。D-Glucose 6-Phosphate是细胞中的常见分子,进入细胞的大部分葡萄糖都会以这种方式被磷酸化,它位于两个主要代谢途径的起点:糖酵解和磷酸戊糖途径[2]。D-Glucose 6-Phosphate还可以转化为糖原或淀粉储存在细胞中[3]。D-Glucose 6-Phosphate可作为底物用于测定重组甘露醇-1-磷酸酶(M1Pase)活性[4]。本产品是水溶液的形式,浓度为1 M(260 mg/ml)。