GlpBio

Ganglioside GM3 Mixture (sodium salt)

目录号: GC43732纯度: >98.00%同义词: 单唾液神经节苷酯GM3; Hematoside; Sialosyllactosylceramide
A mixture of ganglioside GM3
Ganglioside GM3 Mixture (sodium salt)
Cas No.: 54827-14-4
规格价格库存数量操作
1mg¥3,296.00现货
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文献被引

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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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产品描述 Description

Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. It suppresses angiogenesis and reduces proliferation and migration of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 20 μM via inhibition of VEGFR2 and Akt phosphorylation. Ganglioside GM3 induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functioning as an inhibitor of insulin signaling and contributing to insulin resistance in adipocytes. Ganglioside GM3 mixture contains ganglioside GM3 molecular species with C18:1 and C20:1 fatty acyl chains.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
54827-14-4
同义词
单唾液神经节苷酯GM3; Hematoside; Sialosyllactosylceramide
SMILES
O[C@@H]1[C@@H]([C@H]([C@@H](O[C@@H]1CO)O[C@H]2[C@@H]([C@H]([C@@H](O[C@@H]2CO)OC[C@@]([H])([C@](O)(/C=C/CCCCCCCCCCCCC)[H])NC(CCCCCCCCCCCCCCCCC)=O)O)O)O)O[C@]3(O[C@H]([C@@H]([C@H](C3)O)NC(C)=O)[C@@]([H])([C@]([H])(O)CO)O)C([O-])=O.[Na+]
分子式
C59H107N2O21 • Na (for tricosanoyl)
分子量
1203.5 g/mol
溶解性
Chloroform:Methanol (2:1): Soluble; Water: Forms micellar solution
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol