Substrate for the determination of E.coli dihydroorotase (EC 3.5.2.3.), which catalyzes the cyclization of carbamoyl-Asp-OH into L-5,6-dihydroorotate. This enzyme being in the biosynthetic pathway of pyrimidine nucleotides, is an important therapeutic
Carbamoyl-Asp-OH . magnesium salt/Carbamoyl-Asp-OH . dipotassium salt (1:1)
目录号: GA21245纯度: >98.00%
Substrate for the determination of E.coli dihydroorotase (EC 3.5.2.3.), which catalyzes the cyclization of carbamoyl-Asp-OH into L-5,6-dihydroorotate. This enzyme being in the biosynthetic pathway of pyrimidine nucleotides, is an important therapeutic target for the design of new antineoplastic agents. Its activity was assayed spectrophotometrically measuring the increase of absorbance at 230 nm (ε??? = 1170 M?¹cm?¹, Km = 0.47 mM, kcat = 143 s?¹).
Cas No.: 13184-27-5
| 规格 | 价格 | 库存 | 数量 | 操作 |
|---|---|---|---|---|
| 1mg | ¥1,620.00 | 现货 | 1 | |
| 5mg | ¥3,240.00 | 现货 | 1 | |
| 10mg | ¥4,536.00 | 现货 | 1 |
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文献被引
本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
产品描述 Description
产品文档 Product Documents
Purity:>98.00%
化学性质Chemical Properties
CAS 号
13184-27-5
分子式
C10H12K2MgN4O10
分子量
450.73 g/mol
溶解性
H<sub>2</sub>O : 35 mg/mL (198.72 mM; Need ultrasonic)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。
计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度
g/mol