GlpBio

Fodipir (DPDP)

目录号: GC31992纯度: >99.50%同义词: 福地吡; DPDP
Fodipir (DPDP) 是 mangafodipir 的一种活性代谢物，参与 mangafodipir 介导的针对 &7#946;-羟基胆固醇诱导的细胞死亡的细胞保护作用。
Fodipir (DPDP)
Cas No.: 118248-91-2
规格价格库存数量操作
5mg¥450.00现货
1
10mg¥720.00现货
1
25mg¥1,440.00现货
1
50mg¥2,520.00现货
1
100mg¥4,320.00现货
1
10mM (in 1mL Water)¥792.00现货
1
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文献被引

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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death.

Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. Fodipir (Dp-dp; Dipyridoxyl diphosphate; 100 μM) shows the best cytopretective effect on 7β-OH-mediated cell death after treatment for 8 h. Fodipir also reduces 7β-OH-induced cellular ROS production and lysosomal membrane permeabilization (LMP)[1].

[1]. Laskar A, et al. Fodipir and its dephosphorylated derivative dipyridoxyl ethyldiamine are involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. Pharmacology. 2013;92(3-4):182-6.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
118248-91-2
同义词
福地吡; DPDP
SMILES
CC1=NC=C(COP(O)(O)=O)C(CN(CC(O)=O)CCN(CC(C(COP(O)(O)=O)=CN=C2C)=C2O)CC(O)=O)=C1O
分子式
C22H32N4O14P2
分子量
638.46 g/mol
溶解性
H<sub>2</sub>O : 18.18 mg/mL (28.47 mM; Need ultrasonic)
保存条件
Store at 4°C,stored under nitrogen
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol