Flagelin 22 (Flagellin 22), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae[1].
Flagelin 22 is a 22-amino-acid peptide, which corresponds to the highly conserved N-terminal region of flagellin, can induce immunity reaction in various plants such as tomato , potato , tobacco and Arabidopsis thaliana. Moreover, Flagelin 22 significantly induces growth inhibition of algae at a concentration of 1 μM[1]. Treatment of tobacco cells with 200 nMFlagelin 22 induced the production of 13 metabolites. Compared with other microbial-associated molecular pattern (MAMP) molecules and plant hormones, Flagelin 22-treated cells produced a unique metabolite, feruloyltyrosine glycoside isomer 3 [2]. Flagelin 22 (100 nM) activates triggered immunity (PTI) in plants leading to a decrease in the expression of genes involved in the biosynthesis of the growth-promoting hormone brassinosteroid (BR)[3].
References:
[1] Bojun Lu, et al. Defense responses in female gametophytes of Saccharina japonica (Phaeophyta) induced by flg22-derived peptides. Journal of Applied Phycology (2016), 28(3), 1793-1801.
[2] Mhlongo M I, Piater L A, Madala N E, et al. Phenylpropanoid defences in Nicotiana tabacum cells: Overlapping metabolomes indicate common aspects to priming responses induced by lipopolysaccharides, chitosan and flagellin-22[J]. PLoS One, 2016, 11(3): e0151350.
[3] Jiménez-Góngora T, Kim SK, Lozano-Durán R, Zipfel C. Flg22-Triggered Immunity Negatively Regulates Key BR Biosynthetic Genes. Front Plant Sci. 2015 Nov 9;6:981.
Flagelin 22 (Flagellin 22)是细菌鞭毛蛋白的片段，是植物和藻类的有效诱导剂[1]。
Flagelin 22是一种由22个氨基酸组成的肽，对应于鞭毛蛋白高度保守的N端区域，可在番茄、马铃薯、烟草和拟南芥等多种植物中诱导免疫反应，并且，Flagelin 22在1μM的浓度下显著诱导藻类的生长抑制[1]。使用200 nM的Flagelin 22处理烟草细胞可诱导产生13种代谢物，相较于其他微生物相关分子模式（MAMP）分子和植物激素，Flagelin 22处理的细胞会产生一种独特的代谢物阿魏酰酪胺糖苷异构体3[2]。Flagelin 22（100 nM）可激活植物中的触发免疫（PTI）导致生长促进激素油菜素内酯（BR）生物合成基因的表达减少[3]。