ER 50891 quarterdrate is a potent antagonist of retinoic acid receptor α(RARα). ER 50891 quarterdrate significantly attenuates ATRA's inhibitive effects on BMP 2-induced osteoblastogenesis.
References:
[1]. Batran RZ, et al. New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis, homology modeling, dynamic simulations and modulation of Gq/Gs signaling pathways. Bioorg Chem. 2021;111:104817.