E3 Ligase Ligand-Linker Conjugates 21

目录号: GC33103纯度: >98%同义词: Cereblon Ligand-Linker Conjugates 3 ; E3 Ligase Ligand-Linker Conjugates 14
E3 Ligase Ligand-Linker Conjugates 21 (Cereblon Ligand-Linker Conjugates 3) 是一种合成的 E3 连接酶配体-接头偶联物,其中包含用于 PROTAC 技术的基于 Thalidomide 的 cereblon 配体和 3 单元 PEG 接头。

E3 Ligase Ligand-Linker Conjugates 21
Cas No.: 1957236-20-2
规格价格库存数量操作
5mg¥450.00现货
1
10mg¥630.00现货
1
25mg¥900.00现货
1
50mg¥1,620.00现货
1
100mg¥2,520.00现货
1

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产品描述 Description

E3 Ligase Ligand-Linker Conjugates 21 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.

E3 Ligase Ligand-Linker Conjugates 21 is composed of Degron (E3 ubiquitin ligase) and a linker, and they are used in PROTAC technology. E3 Ligase Ligand-Linker Conjugates 21 binds to the targeting ligand to induce the target protein (including BRD4, BRD2, and BRD3) degradation[1].

[1]. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017007612 A1

产品文档 Product Documents

化学性质Chemical Properties

CAS 号
1957236-20-2
同义词
Cereblon Ligand-Linker Conjugates 3 ; E3 Ligase Ligand-Linker Conjugates 14
SMILES
NCCOCCOCCOCCNC(COC1=C(C2=CC=C1)C(N(C(CCC3=O)C(N3)=O)C2=O)=O)=O
分子式
C23H30N4O9
分子量
506.51 g/mol
溶解性
Soluble in DMSO
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol