GlpBio

(E/Z)-BCI

目录号: GC25000纯度: >98%同义词: BCI, NSC 150117
COASDSData Sheet
(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.
(E/Z)-BCI
Cas No.: 15982-84-0
规格价格库存数量操作
5mg¥1,926.00现货
1
25mg¥6,153.00现货
1
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产品描述 Description

(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.

[1] Jong-Woon Shin, et al. Sci China Life Sci. 2018 Oct;61(10):1243-1253. [2] Vasiliy N Korotchenko, et al. Chembiochem. 2014 Jul 7;15(10):1436-45.

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
15982-84-0
同义词
BCI, NSC 150117
分子式
C22H23NO
分子量
317.42 g/mol
溶解性
DMSO: 63 mg/mL (198.48 mM);Water: Insoluble;Ethanol: 20 mg/mL (63.01 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol