Difluorinated H2S Fluorescent Probe 1

Difluorinated H₂S probe 1 is a fluorescent probe for hydrogen sulfide (H₂S).¹ It selectively fluoresces in the presence of H₂S over Zn²⁺, Fe³⁺, S₂O₃^2-, ClO^-, SO₃^2-, H₂O₂, NO₂^-, cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) when used at a concentration of 1 µM. Difluorinated H₂S probe 1 displays excitation/emission maxima of 365/450 nm, respectively.

1.Zhang, J., Gao, Y., Kang, X., et al.o,o-Difluorination of aromatic azide yields a fast-response fluorescent probe for H2S detection and for improved bioorthogonal reactionsOrg. Biomol. Chem.15(19)4212-4217(2017)