GlpBio

Dabsyl chloride (DABS-Cl)

目录号: GC30077纯度: >98.00%同义词: 磺酰氯; DABS-Cl
Dabsyl chloride (DABS-Cl) 是一种胺衍生剂，能够产生稳定的产品，可以在 460 nm 分光光度法上轻松监测； Dabsyl chloride (DABS-Cl) 也用于标记氨基酸。
Dabsyl chloride (DABS-Cl)
Cas No.: 56512-49-3
规格价格库存数量操作
50mg¥270.00现货
1
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产品描述 Description

Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids.

Dabsyl chloride can give rise to mono-Dabsyl and bis-Dabsyl derivatives in the presence of multiple amino groups. Furthermore with respect to OPA derivatization, Dabsyl chloride can react with primary and also with secondary amines[1].

[1]. Francioso A, et al. HPLC Determination of Bioactive Sulfur Compounds, Amino Acids and Biogenic Amines in Biological Specimens. Adv Exp Med Biol. 2017;975:535-549.

实验参考方法 Experimental Reference Method

Cell experiment:

Selected mouse brain samples from either cortical or striatal regions (100 mg wet weight) and neuroblastoma cells (SH-SY5Y) pellet derived from 25 cm2 flask are treated with 500 μL of 0.1 M HCl containing 0.2% TDGA, sonicated for 10 min (only for brain tissue), and then centrifuged at 14000 g for 30 min. The supernatant is freeze-dried. 50 μL of reaction buffer and 100 μL of 15 mM Dabsyl chloride are added to the tube and derivatized.

References:

[1]. Francioso A, et al. HPLC Determination of Bioactive Sulfur Compounds, Amino Acids and Biogenic Amines in Biological Specimens. Adv Exp Med Biol. 2017;975:535-549.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
56512-49-3
同义词
磺酰氯; DABS-Cl
SMILES
O=S(C1=CC=C(/N=N/C2=CC=C(N(C)C)C=C2)C=C1)(Cl)=O
分子式
C14H14ClN3O2S
分子量
323.8 g/mol
溶解性
DMSO: ≥ 5.2 mg/mL (16.06 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol