Cy7 DiC18 (DiIC 18(7); DiR) is a lipophilic long-chain carbocyanine dye that produces near-infrared fluorescence and is widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins. The two long 18-carbon chains of DiR insert into the cell membrane, resulting in specific and stable cell staining with little dye transfer between cells. DiR exhibits pronounced infrared fluorescence, which facilitates multicolor imaging and flow cytometry analysis of living cells. DiR is of great significance in in vivo imaging or tracking. The emitted infrared light can efficiently pass through cells and tissues, and the background fluorescence level in the infrared range is very low[1].
Cy7 DiC18（DiIC 18（7）; DiR）是一种亲脂性长链羰花青染料, 产生近红外荧光，被广泛用作Di来标记细胞，细胞器，脂质体，病毒和脂蛋白。DiR的两条长18碳链插入细胞膜，导致特异和稳定的细胞染色，细胞之间几乎没有染料转移。DiR表现出明显的红外荧光，有利于活细胞的多色成像和流式细胞术分析。DiR在体内活体成像或者示踪中意义非凡，所发射的红外光可以高效地穿过细胞和组织，并且在红外光范围内的本底荧光水平很低[1]
References:
[1]. Shiyan Fu,Ruihao Yang,Junjie Ren,Jiahui Liu,LeiZhang,Zhigang Xu,Yuejun Kang,and Peng Xue.Catalytically Active CoFe204 Nanoflowers for Augmented Sonodynamic and Chemodynamic Combination Therapy with Elicitation of Robust Immune Response.ACS Nano Article ASARDOI: 10.1021/acsnano.1c03128.