GlpBio

Chimmitecan

目录号: GC72859纯度: >98.00%同义词: (S)-9-Allyl-10-Hydroxycamptothecin
Chimmitecan（（S）-9-烯丙基-10-羟基喜树碱）是一种新型的9-小烷基取代的亲脂性喜树碱，是拓扑异构酶I的强效抑制剂。
Chimmitecan
Cas No.: 185425-25-6
规格价格库存数量操作
1mg¥666.00现货
1
5mg¥1,632.00现货
1
10mg¥2,340.00现货
1
25mg¥3,859.00现货
1
50mg¥5,310.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Chimmitecan ((S)-9-Allyl-10-droxycamptothecin), a novel 9-small-alkyl-substituted lipophilic Camptothecin , is a potent inhibitor of topoisomerase I. Chimmitecan exhibits anticancer activity.

References:
[1]. Huang M, et, al. Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo. Clin Cancer Res. 2007 Feb 15;13(4):1298-307.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
185425-25-6
同义词
(S)-9-Allyl-10-Hydroxycamptothecin
分子式
C23H20N2O5
分子量
404.42 g/mol
溶解性
DMSO : 125 mg/mL (309.08 mM; Need ultrasonic)
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol