Carbamazepine-d10 is a stable isotope-labeled internal standard compound used as an internal standard in quantitative analysis for GC-MS, LC/MS, and high-throughput desorption electrospray ionization (DESI)[1-2]. Carbamazepine-d10 has been widely used as a reference substance to develop new identification methods for detecting related compounds in water environments, and the presence of carbamazepine-d10 enables the accurate measurement of the original carbamazepine content and the correction of differences in extraction efficiency or instrument response[3].
References:
[1] Miossec C, Lanceleur L, Monperrus M. Multi‐residue analysis of 44 pharmaceutical compounds in environmental water samples by solid‐phase extraction coupled to liquid chromatography‐tandem mass spectrometry[J]. Journal of separation science, 2019, 42(10): 1853-1866.
[2] Manicke N E, Kistler T, Ifa D R, et al. High-throughput quantitative analysis by desorption electrospray ionization mass spectrometry[J]. Journal of the American Society for Mass Spectrometry, 2011, 20(2): 321-325.
[3] Jeon D R, Kim Y E, Im J K, et al. Non-Targeted Screening and Identification of the Transformation Pathway of Carbamazepine in the Saemangeum Watershed, Republic of Korea[J]. International Journal of Molecular Sciences, 2024, 25(22): 11947.
Carbamazepine-d10是一种稳定同位素标记的内标化合物，在定量分析中用作GC-MS、LC/MS和高通量解吸电喷雾电离（DESI）分析的内标[1-2]。Carbamazepine-d10已广泛用作参考物质，以开发用于检测水环境中相关化合物的新鉴定方法，并且Carbamazepine-d10的存在可实现对原始Carbamazepine含量的准确测定，并可校正提取效率或仪器响应的差异[3]。