Calf thymus DNA is high-quality double-stranded template DNA isolated from the thymus of male and female calves [1]. DNA is usually a major cellular target for the study of small molecules of biological importance, such as carcinogens, steroids, and various drugs [2]. Calf thymus DNA can be used as a standard for DNA quantification, as a substrate for DNA polymerase analysis, and as a carrier DNA for related precipitation analysis [3].
References:
[1] Liu F, et al. Cytotoxicity of Aconitum alkaloid and its interaction with calf thymus DNA by multi-spectroscopic techniques. Sci Rep. 2017 Nov 6;7(1):14509.
[2] Zhang G, Hu X, Pan J. Spectroscopic studies of the interaction between pirimicarb and calf thymus DNA. Spectrochim Acta A Mol Biomol Spectrosc. 2011;78(2):687-694.
[3] Pan LL, Niu W, Fang X, et al. Clostridium butyricum Strains Suppress Experimental Acute Pancreatitis by Maintaining Intestinal Homeostasis [published online ahead of print, 2019 Apr 29]. Mol Nutr Food Res. 2019;e1801419.
Calf thymus DNA是从雄性和雌性小牛的胸腺中分离出的高质量双链模板DNA[1]。DNA 通常是生物学重要性小分子研究的主要细胞靶点，如致癌物、类固醇以及多种药物 [2]。Calf thymus DNA可作为一种标准品用于DNA的定量，作为一种底物用于DNA聚合酶分析，还可作为一种载体DNA用于相关沉淀分析 [3]。