GlpBio

C22:1 1-Deoxyceramide (m18:1/22:1)

目录号: GC47002纯度: >95.00%同义词: C22:1(13Z) 1-Deoxyceramide, C22:1 Ceramide (m18:1/22:1(13Z)), Cer(m18:1/22:1(13Z)), N-13Z-docosenoyl-1-deoxy-4,5-dihydro-Sphingosine
A neuropeptide with diverse biological activities
C22:1 1-Deoxyceramide (m18:1/22:1)
Cas No.: N/A
规格价格库存数量操作
1 mg¥3,562.00现货
1
5 mg¥9,798.00现货
1
电话: 400-920-5774Email: sales@glpbio.cn

文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

C22:1 1-Deoxyceramide (m18:1/22:1) is a long-chain atypical ceramide containing a 1-deoxysphingosine (m18:1(4E)) backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2

1.Steiner, R., Saied, E.M., Othman, A., et al.Elucidating the chemical structure of native 1-deoxysphingosineJ. Lipid Res.57(7)1194-1203(2016) 2.Alecu, I., Othman, A., Penno, A., et al.Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathwayJ. Lipid Res.58(1)60-71(2017)

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
N/A
同义词
C22:1(13Z) 1-Deoxyceramide, C22:1 Ceramide (m18:1/22:1(13Z)), Cer(m18:1/22:1(13Z)), N-13Z-docosenoyl-1-deoxy-4,5-dihydro-Sphingosine
SMILES
C[C@H](NC(CCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@H](O)/C=C/CCCCCCCCCCCCC
分子式
C40H77NO2
分子量
604 g/mol
溶解性
DMF: >20 mg/ml,DMSO: >20 mg/ml,Ethanol: >30mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml,PBS (pH 7.2): <50μg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol