C18:1 Ceramide (d18:1/18:1(9Z)) is a natural sphingosine-oleic acid sphingamide isoform [1]. C18:1 Ceramide (d18:1/18:1(9Z)) is often used as a mass spectrometry standard and is widely used in metabolic disease research and nano-delivery systems [2-3].
References:
[1]. Lerche, S., Wurster, I., Valente, E. M., et al. CSF d18: 1 sphingolipid species in Parkinson disease and dementia with Lewy bodies with and without GBA1 variants. npj Parkinson's Disease, 10(1), 198.
[2]. Sen, P., Andrabi, S. B. A., et al. Quantitative analysis and genome-scale modeling of human CD4+ T-cell differentiation reveals subset-specific regulation of glycosphingolipid pathways. bioRxiv, 2021-01.
[3]. Narváez-Rivas M, Vu N, Chen GY, et al. Off-line mixed-mode liquid chromatography coupled with reversed phase high performance liquid chromatography-high resolution mass spectrometry to improve coverage in lipidomics analysis. Anal Chim Acta. 2017 Feb 15; 954: 140-150.
C18:1 Ceramide (d18:1/18:1(9Z))是一种天然鞘氨醇与油酸结合的鞘酰胺亚型 [1]。C18:1 Ceramide (d18:1/18:1(9Z))常作为质谱分析标准品，并在代谢疾病研究与纳米投递体系中广泛使用 [2-3]。