BODIPY aminoacetaldehyde (BAAA) is a fluorescent substrate for both murine and human aldehyde dehydrogenase (ALDH). BODIPY aminoacetaldehyde consists of an aminoacetaldehyde moiety bonded to the BODIPY fluorochrome and can be used to label stem cells[1].
When combined with inhibition of multidrug resistance, a population termed the SSCloALDHbr population could be readily fractionated from umbilical cord blood (UCB) mononuclear cells on the basis of high BODIPY aminoacetaldehyde (BAAA) staining intensity and low orthogonal light scattering[1].
[1]. R W Storms, et al. Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9118-23.