Biotin-PEG3-benzophenone is biotin-labeled Benzophenone . Benzophenone is an endogenous metabolite and a photosensitizer that has been implicated in photosensitive damage to DNA. Benzophenone causes nucleobase oxidation, formation of cyclobutane-pyrimidine dimers, single-strand breaks, DNA-protein cross-links or abasic sites, different pathologies that may occur in nucleosides, oligonucleotides or DNA .
References:
[1]. Cuquerella MC, Lhiaubet-Vallet V, Cadet J, Miranda MA. Benzophenone photosensitized DNA damage. Acc Chem Res. 2012 Sep 18;45(9):1558-70.
















