B-cell Activating Factor Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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BAFF Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17007 Dalton. The BAFF is purified by proprietary chromatographic techniques.
| Purity | Greater than 95.00%. | Source | HEK293 |
| Phycical Appearance | Solution Protein. | Shipping Condition | Shipped with dry ice. |
| Synonyms | BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20; TNFSF13B; B-cell Activating Factor. | ||
| Amino Acid Sequence | MAVQGPEETV TQDCLQLIAD SETPTIQKGS YTFVPWLLSF KRGSALEEKE NKILVKETGY FFIYGQVLYT DKTYAMGHLI QRKKVHVFGD ELSLVTLFRC IQNMPETLPN NSCYSAGIAK LEEGDELQLA IPRENAQISL DGDVTFFGAL KLL. | ||
| Apparent Molecular Weight | 51/17.0kDa | ||
| Stability | Store at -80°C .Please prevent freeze-thaw cycles. | ||
| Formulation | protein concentration: 0.211 mg/mL, PBS pH: 7.4. | ||
BAFF binds to tnfrsf13b/taci and tnfrsf17/bcma. Tnfsf13/april binds to the same 2 receptors, together, they form a 2 ligands -2 receptors pathway involved in the stimulation of b- and t-cell function and the regulation of humoral immunity.A third b-cell specific baff-receptor (baffr/br3) promotes the survival of mature b-cells and the b-cell response.B Lymphocyte Stimulator functions as a potent B-cell growth factor in costimulation assays. Administration of BAFF Human recombinant to mice disrupts splenic B-cell and T-cell zones and results in elevated levels of serum immunoglobulin.
Store at -80°C .Please prevent freeze-thaw cycles.