GlpBio

Auxinole

目录号: GC30028纯度: >99.50%
Auxinole is a potent auxin antagonist that binds to TIR1 and blocks the formation of the TIR1-IAA-Aux/IAA complex. Auxinole is an OsTIR1 inhibitor that suppresses leaky degradation of degron-fused proteins.
Auxinole
Cas No.: 86445-22-9
规格价格库存数量操作
1mg¥327.00现货
1
5mg¥720.00现货
1
10mg¥1,107.00现货
1
25mg¥2,228.00现货
1
50mg¥3,317.00现货
1
100mg¥4,892.00现货
1
10mM (in 1mL DMSO)¥509.00现货
1
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文献被引

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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Auxinole is a potent auxin antagonist that binds to TIR1 and blocks the formation of the TIR1-IAA-Aux/IAA complex. Auxinole is an OsTIR1 inhibitor that suppresses leaky degradation of degron-fused proteins.

Auxinole causes reduction in IAA-triggered depolarization in root hair cells. Auxinole (20??M) also represses the transient increase in [Ca2+]cyt completely, and blocks Ca2+ response.[4]

[1] Denbigh GL, et al. Am J Bot. 2020 Apr;107(4):577-586. [2] Yesbolatova A, et al. Methods. 2019 Jul 15;164-165:73-80. [3] Yu H, et al. Plant Physiol. 2013 May;162(1):295-303.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
86445-22-9
SMILES
O=C(O)C(CC(C1=CC=C(C)C=C1C)=O)C2=CNC3=C2C=CC=C3
分子式
C20H19NO3
分子量
321.37 g/mol
溶解性
DMSO : ≥ 125 mg/mL (388.96 mM);Ethanol : 12.5 mg/mL (38.90 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol