ARC186 (sodium) is an unconjugated 40KDa PEG aptamer with a sequence identical to 0 Avacincaptad pegol (ARC1905) sodium. ARC1905 is highly potent complement inhibitors that function by blocking the convertase-catalyzed activation of C5.
References:
[1]. Aptamer therapeutics useful in the treatment of complement-related disorders. WO2006088888A2.
















