GlpBio

Arachidonoyl-1-thio-Glycerol

目录号: GC42844纯度: >95.00%同义词: 1SArachidonoyl1mercapto2,3propanediol
A chromogenic substrate for measurement of monoacylglycerol lipase activity
Arachidonoyl-1-thio-Glycerol
Cas No.: 1309664-54-7
规格价格库存数量操作
1mg¥447.00现货
1
5mg¥1,866.00现货
1
10mg¥3,326.00现货
1
25mg¥7,223.00现货
1
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文献被引

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产品描述 Description

2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the central cannabinoid (CB1) receptor. It is present at relatively high levels in the central nervous system and is the most abundant molecular species of monoacylglycerol found in rat brain. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to arachidonic acid and glycerol, thereby terminating its biological actions. Arachidonoyl-1-thio-glycerol is a thioester substrate analog of 2-arachidonoyl glycerol that can be utilized for the measurement of MAGL activity. Hydrolysis of the thioester bond by MAGL generates a free thiol that reacts rapidly with the chromogenic reagent DTNB (Ellman's reagent) resulting a yellow product with an absorbance maximum at 412 nm.

产品文档 Product Documents

Purity:>95.00%Appearance:A solution in acetonitrile

化学性质Chemical Properties

CAS 号
1309664-54-7
同义词
1SArachidonoyl1mercapto2,3propanediol
SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)SCC(O)CO
分子式
C23H38O3S
分子量
394.6 g/mol
溶解性
DMF: 20 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:2): .25 mg/ml
保存条件
Store at -80°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol