| 规格 | 价格 | 库存 | 数量 | 操作 |
|---|---|---|---|---|
| 1mg | ¥347.00 | 现货 | 1 | |
| 5mg | ¥765.00 | 现货 | 1 | |
| 10mg | ¥1,233.00 | 现货 | 1 | |
| 25mg | ¥2,475.00 | 现货 | 1 | |
| 50mg | ¥3,690.00 | 现货 | 1 | |
| 100mg | ¥5,265.00 | 现货 | 1 | |
| 10mM (in 1mL DMSO) | ¥614.00 | 现货 | 1 |
AQ-13 dihydrochloride is an aminoquinoline antimalarial drug that is effective against chloroquine-resistant strains of Plasmodium falciparum.
Slight decreases in the PCE/RBC ratio are observed in male and female rats treated with CQ and in females only treated with AQ-13; however, none of these changes is statistically significant[1].
[1]. Riccio ES, et al. Genetic toxicology testing of the antimalarial drugs chloroquine and a new analog, AQ-13. Environ Mol Mutagen. 2001;38(1):69-79.
Animal experiment: | Rats[1]Male and female Sprague-Dawley rats are used and are 8-9 weeks of age at the time of dose administration. Micronucleus evaluations are conducted in conjunction with repeatdose toxicity studies. Rats are orally administered AQ-13 or CQ in water. Rats are given a “loading dose” followed by maintenance doses of one-half the loading dose administered 12 hr later and daily thereafter for 6 additional days[1]. |
References: [1]. Riccio ES, et al. Genetic toxicology testing of the antimalarial drugs chloroquine and a new analog, AQ-13. Environ Mol Mutagen. 2001;38(1):69-79. |
