Antifungal agent 48 (Example 308) is an antifungal agent. Antifungal agent 48 is active against Cryptococcus neoformans with a MIC value of 11 μM.
Antifungal agent 48 (Example 308) (48 h) shows cytotoxicity with a CC50 of 24 μM in HepDES 19 cells[1].
References:
[1]. Maureen J. DONLIN, et al. Patent. Anti-fungal compounds. WO2017184752. 2017-10-26.
















