GlpBio

Ac-LEHD-AMC (trifluoroacetate salt)

目录号: GC18226纯度: >95.00%同义词: Ac-Leu-Glu-His-Asp-AMC, Caspase-9 Substrate
A caspase-9 fluorogenic substrate
Ac-LEHD-AMC (trifluoroacetate salt)
Cas No.: 292633-16-0
规格价格库存数量操作
500μg¥416.00现货
1
1mg¥785.00现货
1
5mg¥2,418.00现货
1
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文献被引

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产品描述 Description

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9.[1]  Upon cleavage by caspase-9, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-9 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

References
[1]. Prudnikov, I.M., and Smirnov, A.N. Short peptide tools for monitoring caspase and proteasome activities in embryonal and adult rat brain lysates: An approach for the differential identification of proteases. J. Biochem. 151(3), 299-316 (2012).

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
292633-16-0
同义词
Ac-Leu-Glu-His-Asp-AMC, Caspase-9 Substrate
化学名
N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine, trifluoroacetate salt
SMILES
CC(C1=CC=C(C=C1O2)NC([C@@H](NC([C@H](CC3=CN=CN3)NC([C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)CCC(O)=O)=O)=O)CC(O)=O)=O)=CC2=O.FC(F)(C(O)=O)F
分子式
C33H41N7O11.XCF3COOH
分子量
711.7 g/mol
溶解性
1mg/mL in water
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol