GlpBio

α-Cortolone

目录号: GC49838纯度: >98.00%同义词: Β-皮甾酮四醇
A metabolite of cortisol
α-Cortolone
Cas No.: 516-42-7
规格价格库存数量操作
1 mg¥1,379.00现货
1
5 mg¥6,211.00现货
1
10 mg¥10,347.00现货
1
25 mg¥17,238.00现货
1
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文献被引

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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

α-Cortolone is a metabolite of the glucocorticoid cortisol .1 It is formed from cortisol by 20α-hydroxysteroid dehydrogenase (20α-HSD) via a tetrahydrocortisone intermediate. Urinary levels of α-cortolone are decreased in patients with severe anorexia nervosa and in postmenopausal women with endometrial adenocarcinoma compared to postmenopausal women without endometrial adenocarcinoma.2,3

1.Espiard, S., McQueen, J., Sherlock, M., et al.Improved urinary cortisol metabolome in Addison disease: A prospective trial of dual-release hydrocortisoneJ. Clin. Endocrinol. Metab.106(3)814-825(2021) 2.Wassif, W.S., McLoughlin, D.M., Vincent, R.P., et al.Steroid metabolism and excretion in severe anorexia nervosa: Effects of refeedingAm. J. Clin. Nutr.93(5)911-917(2011) 3.Bufa, A., BÍrÓ, I., PoÓr, V., et al.Altered urinary profiles of endogenous steroids in postmenopausal women with adenocarcinoma endometriiGynecol. Endocrinol.26(1)10-15(2010)

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
516-42-7
同义词
Β-皮甾酮四醇
SMILES
C[C@@]12[C@](CC[C@]2(O)[C@@H](O)CO)([H])[C@@]3([H])[C@@](C(C1)=O)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C
分子式
C21H34O5
分子量
366.5 g/mol
溶解性
DMSO: soluble,Ethanol: soluble
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

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g/mol