GlpBio

8-iso Prostaglandin F3α

目录号: GC18829纯度: >98.00%同义词: 8-epi PGF3α
An isoprostane produced from the free-radical peroxidation of EPA
8-iso Prostaglandin F3α
Cas No.: 7045-31-0
规格价格库存数量操作
25μg¥4,258.00现货
1
50μg¥7,660.00现货
1
100μg¥13,574.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of human platelet shape change, where 8-iso PGF2α has an ED50 value of 1 uM. [1]

Reference:
[1]. Praticò, D., Smith, E.M., Violi, F., et al. Local amplification of platelet function by 8-epi prostaglandin F2α is not mediated by thromboxane receptor isoforms. The Journal of Biological Chemisty 271, 14916-14924 (1996).

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
7045-31-0
同义词
8-epi PGF3α
化学名
9α,11α,15S-trihydroxy-(8β)-prosta-5Z,13E,17Z-trien-1-oic acid
SMILES
O[C@@H]1[C@@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)C/C=C\CC)[C@H](O)C1
分子式
C20H32O5
分子量
352.5 g/mol
溶解性
>100 mg/ml (from PGF2a) in DMSO, >100 mg/ml (from PGF2a) in DMF, >100 mg/ml (from PGF2a) in Ethanol
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol