GlpBio

8-iso Prostaglandin A2

目录号: GC18781纯度: >98%同义词: A2 Isoprostane, 15-A2t-IsoP, 15-A2t-Isoprostane, 8-epi PGA2, 8-iso PGA2
COASDSData Sheet
An isoprostane
8-iso Prostaglandin A2
Cas No.: 474391-66-7
规格价格库存数量操作
1mg¥2,603.00现货
1
100µg¥493.00现货
1
500µg¥1,540.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Isoprostanes are prostaglandin (PG)-like compounds produced in vivo by free radical-catalyzed peroxidation of arachidonoyl-containing lipids. 8-iso PGA2 is one of several isoprostanes produced from peroxidation of arachidonic acid esterified in phospholipids. 8-iso PGA2 is the dehydration product of 8-iso PGE2, a potent renal vasoconstrictor. Evidence for the in vivo production of 8-iso PGA2 has been shown in rat liver under conditions of oxidative stress. There are no published studies of the pharmacological properties of 8-iso PGA2.

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
474391-66-7
同义词
A2 Isoprostane, 15-A2t-IsoP, 15-A2t-Isoprostane, 8-epi PGA2, 8-iso PGA2
化学名
9-oxo-15S-hydroxy-(8β)-prosta-5Z,10,13E-trien-1-oic acid
SMILES
O=C1[C@@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)C=C1
分子式
C20H30O4
分子量
334.5 g/mol
溶解性
DMF: >75 mg/mL (From PGA1),DMSO: >50 mg/mL (From PGA1),Ethanol: >100 mg/mL (From PGA1),PBS pH 7.2: >2.4 mg/mL (From PGA1)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol