GlpBio

7-Methylguanosine 5’-diphosphate sodium

目录号: GC62817纯度: >97.00%同义词: 7-Methyl-GDP sodium; m7GDP sodium
7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium，一种 cap 类似物，可以用来合成 mRNA cap 类似物。
7-Methylguanosine 5’-diphosphate sodium
Cas No.: 104809-16-7
规格价格库存数量操作
1 mg¥1,485.00现货
1
5 mg¥4,455.00现货
1
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文献被引

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产品描述 Description

7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues[1].

7-Methylguanosine 5’-diphosphate sodium inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA[1].T. brucei mRNA decapping enzyme (TbDcp2) that cleaves 7-Methylguanosine 5’-diphosphate sodium from capped RNA to generate pRNA, a substrate for TbCe1[2].

[1]. Sonenberg N, et al. Nonspecific effect of m7GMP on protein-RNA interactions. J Biol Chem. 1978;253(19):6630-6632.
[2]. Ignatochkina AV, et al. The messenger RNA decapping and recapping pathway in Trypanosoma. Proc Natl Acad Sci U S A. 2015;112(22):6967-6972.

产品文档 Product Documents

Purity:>97.00%

化学性质Chemical Properties

CAS 号
104809-16-7
同义词
7-Methyl-GDP sodium; m7GDP sodium
分子式
C11H16N5NaO11P2
分子量
479.21 g/mol
溶解性
H<sub>2</sub>O : 50 mg/mL (104.34 mM; Need ultrasonic and warming)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol