GlpBio

6-Phosphogluconic acid trisodium

目录号: GC65015纯度: >98.00%同义词: 6-磷酸葡萄糖酸三钠盐
6-Phosphogluconic acid trisodium 是一种有效的，竞争性磷酸葡萄糖异构酶 (PGI) 抑制剂，对 6-磷酸葡萄糖和 6-磷酸果糖的 Ki 值分别为 48 μM 和 42 μM。6-Phosphogluconic acid trisodium 是一种内源性代谢物 (endogenous metabolite)。
6-Phosphogluconic acid trisodium
Cas No.: 53411-70-4
规格价格库存数量操作
25mg¥720.00现货
1
50mg¥963.00现货
1
100mg¥1,767.00现货
1
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文献被引

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    183(7):1867-1883 (2020)
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产品描述 Description

6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite[1][2].

6-Phosphogluconic acid trisodium (0.5-2.0 mM) completely inhibits the activity of PGI with glucose 6-phosphate (0.05- 0.5 mM) as the substrate[1].

[1]. Gaitonde MK, et al. Effect of 6-phosphogluconate on phosphoglucose isomerase in rat brain in vitro and in vivo. J Neurochem. 1989 May;52(5):1348-52.
[2]. Hitosugi T, et al. Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer Cell. 2012 Nov 13;22(5):585-600.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
53411-70-4
同义词
6-磷酸葡萄糖酸三钠盐
分子式
C6H10Na3O10P
分子量
342.08 g/mol
溶解性
H<sub>2</sub>O : 125 mg/mL (365.41 mM; Need ultrasonic)
保存条件
4&#176;C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol