GlpBio

6α-Methylprednisolone 21-hemisuccinate

目录号: GC42587纯度: >98.00%同义词: 甲基泼尼松龙琥珀酸酯; Methylprednisolone hydrogen succinate
A prodrug form of methylprednisolone
6α-Methylprednisolone 21-hemisuccinate
Cas No.: 2921-57-5
规格价格库存数量操作
5mg¥133.00现货
1
10mg¥210.00现货
1
25mg¥335.00现货
1
50mg¥448.00现货
1
100mg¥616.00现货
1
200mg¥945.00现货
1
10mM (in 1mL DMSO)¥139.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Methylprednisolone is a synthetic glucocorticoid that has anti-inflammatory and immunosuppressant effects through the glucocorticoid receptor. The methyl group reduces specific binding to corticosteroid-binding globulin, which may allow better tissue penetration, compared to that of prednisolone. 6α-Methylprednisolone 21-hemisuccinate is a prodrug for methylprednisolone. This compound has superior water solubility compared to the active glucocorticoid.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
2921-57-5
同义词
甲基泼尼松龙琥珀酸酯; Methylprednisolone hydrogen succinate
SMILES
O=C1C=C[C@@]2(C)C([C@@H](C)C[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(COC(CCC(O)=O)=O)=O)=C1
分子式
C26H34O8
分子量
474.6 g/mol
溶解性
DMF: 3 mg/ml,DMSO: 5 mg/ml,DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol