5-Azidometl-2'-deoxyuridine (5-AmdU) is a purine nucleoside analog. 5-Azidometl-2'-deoxyuridine demonstrates effective radiosensitization in EMT6 tumor cells.. 5-Azidometl-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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