5,7,8-Trimethoxydictamnine is a quinoline alkaloid that has been found in Rutaceae and has antimalarial activity.1 It is active against chloroquine-sensitive and -resistant strains of P. falciparum (IC50s =19.9 and 5.72 µg/ml, respectively).
1.Basco, L.K.M., S., Skaltsounis, A.-L., Ravvelomanantsoa, N., et al.In vitro activities of furoquinoline and acridone alkaloids against Plasmodium falciparumAntimicrob. Agents Chemother.38(5)1169-1171(1994)