(2R,3S)-N-Cbz-6-oxo-2,3-Diphenylmorpholine is a chiral building block.1,2,3 It has been used in the stereoselective synthesis of fluorescent and non-fluorescent amino acids.
1.Reno, D.S., Lotz, B.T., and Miller, M.J.Asymmetric aldol reactions using boron enolates of chiral oxazinones, synthesis of L-allo-threonineTetrahedron Lett.31(6)827-830(1990) 2.Schuerman, M.A., Keverline, K.I., and Hiskey, R.G.Chiral synthesis of L-γ-carboxyglutamic acid (L-Gla)Tetrahedron Lett.36(6)825-828(1995) 3.Sui, G., Kele, P., Orbulescu, J., et al.Synthesis of a coumarin based fluorescent amino acidLett. Pept. Sci.847-51(2001)