GlpBio

11β-13,14-dihydro-15-keto Prostaglandin F2α

目录号: GC40577纯度: >95.00%同义词: 11β13,14dihydro15keto PGF2α, 11-epi-13,14-dihydro-15-keto PGF2α
A metabolite of PGD2
11β-13,14-dihydro-15-keto Prostaglandin F2α
Cas No.: 107615-77-0
规格价格库存数量操作
500μg¥6,784.00现货
1
50μg¥878.00现货
1
100μg¥1,648.00现货
1
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文献被引

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    641, 529–536 (2025)
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    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

11β-13,14-dihydro-15-keto Prostaglandin F2α (11β-13,14-dihydro-15-keto PGF2α) is a metabolite of Prostaglandin D2 (PGD2) in the 15-hydroxy PGDH pathway. Infusion or inhalation of tritiated PGD2 in normal males results in the appearance of peak levels of both 11β-PGF2α, as the immediate product, and 11β-13,14-dihydro-15-keto PGF2α in the plasma within 10 minutes. Homogenates of human lung metabolize PGD2 first to 11β-PGF2α and then to 11β-15-keto-PGF2α in the presence of NAD+, but no 11β-13,14-dihydro-15-keto PGF2α. Guinea pig liver and kidney homogenates metabolize PGD2 to 11β-13,14-dihydro-15-keto PGF2α, via 11β-PGF2α, in the presence of NAD+ and NADP+.

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
107615-77-0
同义词
11β13,14dihydro15keto PGF2α, 11-epi-13,14-dihydro-15-keto PGF2α
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](CCC(CCCCC)=O)[C@@H](O)C1
分子式
C20H34O5
分子量
354.5 g/mol
溶解性
10 mM Na2CO3: >6.5 mg/ml (from PGF2a),DMF: >100 mg/ml (from PGF2a),DMSO: >100 mg/ml (from PGF2a),Ethanol: >100 mg/ml (from PGF2a),PBS pH 7.2: >10 mg/ml (from PGF2a)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol