1-Metladenosine-d3 drochloride is the drochloride salt form of deuterium labeled 1-Metladenosine . 1-Metladenosine is an RNA modification that can serve as a tumor marker, with elevated levels in the body associated with cancer development. Following 1-metladenosine metlation, upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway, driving liver tumorigenesis.
References:
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[4]. Wang Y, et al. N 1-metladenosine metlation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism[J]. Nature communications, 2021, 12(1): 6314.
















