1,5-Anhydro-D-glucitol (1,5-AG) is a monosaccharide and a metabolically inert analog of D-glucose that has been found in a variety of dietary sources including soy, white rice, pasta, vegetables, fish, and tea.1,2 Renal reabsorption of 1,5-AG is blocked by glucose, and serum levels of 1,5-AG are decreased by repeated episodes of hypoglycemia. Serum levels of 1,5-AG have been used as a supplementary glycemic marker to hemoglobin A1c (HbA1c) levels in patients with diabetes mellitus.
1.Dungan, K.M.1,5-anhydroglucitol (GlycoMark) as a marker of short-term glycemic control and glycemic excursionsExpert Rev. Mol. Diagn.8(1)9-19(2008) 2.Kim, W.J., and Park, C.Y.1,5-Anhydroglucitol in diabetes mellitusEndrocrine43(1)33-40(2013)