VUAA1 is an insect odorant co-receptor (Orco) agonist. VUAA1 activates both heteromeric and homomeric Orco-containing channels. VUAA1 can disrupt the destructive behaviors of nuisance insects. VUAA1 can be used for insect olfactory research.
References:
[1]. Corcoran JA, et al. Endogenous insensitivity to the Orco agonist VUAA1 reveals novel olfactory receptor complex properties in the specialist fly Mayetiola destructor. Sci Rep. 2018 Feb 22;8(1):3489.
[2]. Jones PL, et al. Functional agonism of insect odorant receptor ion channels. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8821-5.