trans-Clopenthixol ((E)-Clopenthixol) didrochloride is an antibiotic agent, without neuroleptic effect. trans-Clopenthixol can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro.
References:
[1]. Kristiansen JE, et al. The susceptibility of Plasmodium falciparum in vitro to chlorpromazine and the stereo-isomeric compounds cis(Z)- and trans(E)-clopenthixol. Acta Pathol Microbiol Immunol Scand B. 1985 Jun;93(3):249-51.
[2]. Kristiansen J E, et al. Stereo-isomeric dissociation of the antibacterial and the neuroleptic effect of clopenthixol[J]. Acta pathologica et microbiologica Scandinavica. Section B, Microbiology, 1981, 89(6): 437-438.
















