GlpBio

TbPTR1 inhibitor 2

目录号: GC72510纯度: >99.00%
TbPTR1 inhibitor 2(化合物3a)是PTR1酶抑制剂，对TbPTR1和LmPTR1的ic50分别为34.2和32.9 μM。
TbPTR1 inhibitor 2
Cas No.: 17557-67-4
规格价格库存数量操作
5mg¥160.00现货
1
10mg¥234.00现货
1
25mg¥403.00现货
1
50mg¥637.00现货
1
100mg¥937.00现货
1
200mg¥1,328.00现货
1
10mM (in 1mL DMSO)¥176.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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产品描述 Description

TbPTR1 inhibitor 2 (Compound 3a) is a PTR1 enzyme inhibitor, with IC50s of 34.2 and 32.9 μM for TbPTR1 and LmPTR1. TbPTR1 inhibitor 2 has anti-parasitic activity against T. brucei (IC50: 34.2 μM).

References:
[1]. Linciano P, et al. Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections. J Med Chem. 2019 Apr 25;62(8):3989-4012.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
17557-67-4
分子式
C8H8N2O2S2
分子量
228.29 g/mol
溶解性
DMSO : 125 mg/mL (547.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol