Surfactin C1 is a highly effective and biologically active surfactant that inhibits HL-60 cell-human umbilical vein endothelial cells (HUVECs) adhesion triggered by lipopolysaccharide (LPS)[1]. Surfactin C1 can suppress LPS-induced expression of ICAM-1 and VCAM-1 in HUVECs[1]. Surfactin C1 protects wheat from the wheat blight pathogen and activates salicylic acid and jasmonic acid-dependent defense responses [2].
References:
[1] Takahashi T, Ohno O, Ikeda Y, et al. Inhibition of lipopolysaccharide activity by a bacterial cyclic lipopeptide surfactin[J]. The Journal of Antibiotics, 2006, 59(1): 35-43.
[2] Le Mire G, Siah A, Brisset M N, et al. Surfactin protects wheat against Zymoseptoria tritici and activates both salicylic acid-and jasmonic acid-dependent defense responses[J]. Agriculture, 2018, 8(1): 11.
Surfactin C1是一种高效生物活性表面活性剂, 可显著抑制脂多糖（LPS）诱导的HL-60细胞与人脐静脉内皮细胞（HUVEC）的粘附作用[1]。Surfactin C1能抑制LPS诱导的HUVECs中ICAM-1和VCAM-1的表达[1]。Surfactin C1可保护小麦免受小麦枯病病原体的侵害，并激活水杨酸和茉莉酸依赖性防御反应[2]。