Sodium copper chlorophyllin

目录号: GC32192纯度: >98%同义词: 叶绿素铜钠

叶绿素铜钠对流感病毒和 HIV 具有抗病毒活性，IC50 为 50 至 100 μM 两者。

Cas No.: 28302-36-5

规格	价格	库存	数量	操作
1g	¥446.00	现货	1
10mM (in 1mL Water)	¥491.00	现货	1

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183(7):1867-1883 (2020)
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产品描述 Description

Sodium copper chlorophyllin exerts antiviral activities against Influenza virus and HIV with IC50s of 50 to 100 μM for both of them.

Sodium copper chlorophyllin exhibits influenza virus adsorption at 200 µM (P<0.05). The 50% inhibitory concentration (IC50) and the 50% cytotoxic concentration (CC50) of Sodium copper chlorophyllin lay from 50 to 100 µM and 200 to 400 µM, respectively. Sodium copper chlorophyllin also inhibits HIV adsorption at 2.5 mM (P<0.05). The IC50 and CC50 of Sodium copper chlorophyllin lay from 50 to 100 µM and 200 to 400 µM, respectively[1].

[1]. Akiko Ito, et al. In Vitro Inhibition of Cytopathic Effect of Influenza Virus and Human Immunodeficiency Virus by Bamboo Leaf Extract Solution and Sodium Copper Chlorophyllin. Yonago Acta Med. 2016 Mar; 59(1): 61-65.

实验参考方法 Experimental Reference Method

Cell experiment:

MT-2 cells are pre-incubated to the bamboo leaf extract solution (up to 10%), Sodium copper chlorophyllin (up to 5 mM) or test reagent-free culture medium for 10 min to assess the inhibitory activity at adsorption. The pre-incubated cells are washed extensively to be able to eliminate antiviral activity of test reagents remaining in the culture medium, and then they are exposed to HIV-1LAI (1.3×10-4 TCID50 per cell). In addition to these pre-incubated cells, control wells are prepared to evaluate growth of the cells in a virus-free condition. Then, virus-exposed and mock-exposed cells are cultured in the absence of test reagents for three days. The total viable cells are counted on day 3[1].

References:

产品文档 Product Documents

Purity:>98%

COA SDS Data Sheet

化学性质Chemical Properties

CAS 号

28302-36-5

同义词

叶绿素铜钠

SMILES

[O-]C(CC1=C(C(C([O-])=O)=C(C)C2=CC3=[N]4C(C(C=O)=C3CC)=CC5=C(C=C)C(C)=C6[N-]75)[N-]2[Cu+2]47[N](C8=C6)=C1C(C8C)CCC([O-])=O)=O.[Na+].[Na+].[Na+]

分子式

C₃₄H₂₉CuN₄Na₃O₇

分子量

738.13 g/mol

溶解性

Water : 10 mg/mL (13.55 mM);DMSO : 6.67 mg/mL (9.04 mM)

保存条件

Store at -20°C

General tips

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。

Shipping Condition

评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

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分子量 (MW)

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