GlpBio

SN-38 Glucuronide

目录号: GC49760纯度: >98.00%同义词: SN-38葡糖苷酸,SN-38G
A phase II metabolite of irinotecan
SN-38 Glucuronide
Cas No.: 121080-63-5
规格价格库存数量操作
1mg¥4,050.00现货
1
10mM (in 1mL DMSO)¥25,328.00现货
1
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文献被引

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产品描述 Description

SN-38 Glucuronide is a phase II metabolite of irinotecan .1 It is formed via glucuronidation of the irinotecan phase I metabolite SN-38 by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1.

1.Hirose, K., Kozu, C., Yamashita, K., et al.Correlation between plasma concentration ratios of SN-38 glucuronide and SN-38 and neutropenia induction in patients with colorectal cancer and wild-type UGT1A1 geneOncol. Lett.3(3)694-698(2012)

产品文档 Product Documents

Purity:>98.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
121080-63-5
同义词
SN-38葡糖苷酸,SN-38G
SMILES
CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)C=C51
分子式
C28H28N2O11
分子量
568.5 g/mol
溶解性
DMSO: slightly soluble,Methanol: slightly soluble
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol