[Ser4,Ile8]-Oxytocin (trifluoroacetate salt)

[Ser4,Ile8]-Oxytocin is a neuropeptide and analog of oxytocin . In vivo, [Ser4,Ile8]-oxytocin increases activity of slow-firing oxytocin neurons and triggers the milk ejection reflex in female rats when injected into the third ventricle at a dose of 1 ng. It induces uterine contraction in female rats and prevents penile erection and yawning in male rats. [Ser4,Ile8]-Oxytocin also decreases blood glucose, glucose intolerance, and hyperinsulinemia without affecting body weight in mice with high-fat diet-induced type 2 diabetes.