关于 "Src" 的结果81+ 个结果
- ARQ 531CAS: 2095393-15-8
Nemtabrutinib (ARQ 531, MK-1026) is an ATP-competitive tyrosine kinase inhibitor designed to target BTK with an IC50 of 0.85 nM. It also has a distinct kinase selectivity profile with strong inhibitory activity against several key oncogenic drivers from TEC, Trk and Src family kinases.
- 7-Hydroxy-4-chromone (7-Hydroxychromone)CAS: 59887-89-7
7-Hydroxychromone is an inhibitor of Src kinase with IC50 of <300 μM.
- Target Protein-binding moiety 8CAS: 910297-51-7
Target Protein-binding moiety 8 (N-Deshydroxyethyl BMS-354825) 是 Dasatinib 的代谢物,Dasatinib 是一种多激酶抑制剂,可有效抑制 Bcr-Abl、Src 家族和血小板衍生的生长因子受体激酶。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC31679 | ARQ 531 | 2095393-15-8 | BTK | ||
Nemtabrutinib (ARQ 531, MK-1026) is an ATP-competitive tyrosine kinase inhibitor designed to target BTK with an IC50 of 0.85 nM. It also has a distinct kinase selectivity profile with strong inhibitory activity against several key oncogenic drivers from TEC, Trk and Src family kinases. | |||||
| GC32797 | AD80 | 1384071-99-1 | RET | ||
AD80, a multikinase inhibitor, shows strong activity against human RET (c-RET), BRAF, S6K, and SRC but were much less active than either AD57 or AD58 against mTOR. The IC50 value for RET is 4 nM. | |||||
| GC32825 | eCF506 | 1914078-41-3 | Src | ||
An inhibitor of Src kinases | |||||
| GC32835 | PP58 | 212391-58-7 | PDGFR | ||
PP58是吡啶[2,3-d]嘧啶化合物,抑制PDGFR,FGFR和Src家族活性的IC50值在纳摩尔级。 | |||||
| GC32875 | AZM475271 (M475271) | 476159-98-5 | Src | ||
An inhibitor of c-Src kinase | |||||
| GC32992 | 7-Hydroxy-4-chromone (7-Hydroxychromone) | 59887-89-7 | Src | ||
7-Hydroxychromone is an inhibitor of Src kinase with IC50 of <300 μM. | |||||
| GC33350 | Target Protein-binding moiety 8 | 910297-51-7 | Ligand for Target Protein for PROTAC | ||
Target Protein-binding moiety 8 (N-Deshydroxyethyl BMS-354825) 是 Dasatinib 的代谢物,Dasatinib 是一种多激酶抑制剂,可有效抑制 Bcr-Abl、Src 家族和血小板衍生的生长因子受体激酶。 | |||||
| GC34109 | Tirbanibulin Mesylate (KX2-391 (Mesylate)) | 1080645-95-9 | Microtubule/Tubulin | ||
A Src kinase inhibitor | |||||
| GC34110 | WEHI-345 analog | 1354825-62-9 | Src | ||
WEHI-345(analog)是一种Src抑制剂。 | |||||
