关于 "Src" 的结果81+ 个结果

Nemtabrutinib (ARQ 531, MK-1026) is an ATP-competitive tyrosine kinase inhibitor designed to target BTK with an IC50 of 0.85 nM. It also has a distinct kinase selectivity profile with strong inhibitory activity against several key oncogenic drivers from TEC, Trk and Src family kinases.

AD80, a multikinase inhibitor, shows strong activity against human RET (c-RET), BRAF, S6K, and SRC but were much less active than either AD57 or AD58 against mTOR. The IC50 value for RET is 4 nM.

An inhibitor of Src kinases

PP58是吡啶[2,3-d]嘧啶化合物，抑制PDGFR，FGFR和Src家族活性的IC50值在纳摩尔级。

An inhibitor of c-Src kinase

7-Hydroxychromone is an inhibitor of Src kinase with IC50 of <300 μM.

Target Protein-binding moiety 8 (N-Deshydroxyethyl BMS-354825) 是 Dasatinib 的代谢物，Dasatinib 是一种多激酶抑制剂，可有效抑制 Bcr-Abl、Src 家族和血小板衍生的生长因子受体激酶。

A Src kinase inhibitor

WEHI-345(analog)是一种Src抑制剂。