关于 "Cathepsin" 的结果81+ 个结果
- Z-Val-Val-Arg-AMC . HClCAS: 124485-41-2
Z-Val-Val-Arg-AMC . HCl is a substrate of human and canine cathepsin S. Z-Val-Val-Arg-AMC . HCl is also cleaved by falcipain-related enzymes from Plasmodium species.
- (Asn⁶⁷⁰,Leu⁶⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (667-675)CAS: 150234-52-9
SEVNLDAEF corresponds to the mutant junctional sequence of the amyloid precursor protein (APP) found in a Swedish family with early-onset Alzheimer's disease, therefore referred to as the 'Swedish' mutation (K670N/M671L). The peptide has been used for assaying cleavage at leucine-aspartate by cathepsin G and chymotrypsin, whereas neither cathepsin B, D nor L generated any products.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GA23981 | Z-Val-Val-Arg-AMC . HCl | 124485-41-2 | - | ||
Z-Val-Val-Arg-AMC . HCl is a substrate of human and canine cathepsin S. Z-Val-Val-Arg-AMC . HCl is also cleaved by falcipain-related enzymes from Plasmodium species. | |||||
| GC60960 | JPM-OEt | 262381-84-0 | Cathepsin | ||
JPM-OEt是一种广谱的半胱氨酸组织蛋白酶(cysteinecathepsin)抑制剂。JPM-OEt在活性位点共价结合，并且不可逆地抑制半胱氨酸组织蛋白酶家族。具有抗肿瘤活性。 | |||||
| GC61158 | ONO-5334 | 868273-90-9 | SARS-CoV | ||
ONO-5334是一种强效、选择性和口服活性的组织蛋白酶K(cathepsinK)抑制剂，对人、兔和大鼠组织蛋白酶K的作用值分别为0.10nM、0.049nM和0.85nM。ONO-5334是一种有效的抗SAR-COV-2病毒活性的抗病毒化合物，其EC50值为500nM。ONO-5334有潜力用于骨质疏松症以及COVID-19的相关研究。 | |||||
| GC18315 | Calpain Inhibitor VI | 190274-53-4 | Proteolysis | ||
A calpain and cathepsin inhibitor | |||||
| GC30296 | H-Arg-4MβNA | 60285-94-1 | Others | ||
H-Arg-4MβNA是cathepsinH的底物，可用于凝胶电泳中检测酶活性。 | |||||
| GC45668 | Gly-Arg-AMC (hydrochloride) | 70274-78-1 | Proteolysis | ||
Gly-Arg-AMC (hydrochloride)是组织蛋白酶C(Cathepsin C)的荧光底物。 | |||||
| GC50002 | N-Acetyl-L-leucyl-L-leucyl-L-methional | 145757-50-2 | - | ||
Cathepsin inhibitor | |||||
| GC45599 | Z-Phe-Tyr(tBu)-diazomethylketone | 114014-15-2 | Proteases | ||
An inhibitor of cathepsin L | |||||
| GA20039 | (Asn⁶⁷⁰,Leu⁶⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (667-675) | 150234-52-9 | Amyloid β protein | ||
SEVNLDAEF corresponds to the mutant junctional sequence of the amyloid precursor protein (APP) found in a Swedish family with early-onset Alzheimer's disease, therefore referred to as the 'Swedish' mutation (K670N/M671L). The peptide has been used for assaying cleavage at leucine-aspartate by cathepsin G and chymotrypsin, whereas neither cathepsin B, D nor L generated any products. | |||||