关于 "ROR/RAR/RXR" 的结果31+ 个结果
- Ro 41-5253CAS: 144092-31-9
Ro 41-5253 是一种具有口服活性的选择性维甲酸受体 RARα 拮抗剂。Ro 41-5253 可以与 RARα 结合而不诱导转录或影响 RAR/RXR 异二聚化和 DNA 结合。Ro 415253 可抑制癌细胞增殖并诱导细胞凋亡 (apoptosis)，具有抗肿瘤活性。
- LY 2955303 dihydrochlorideCAS: 2469014-43-3
Potent and selective retinoic acid receptor gamma (RARγ) antagonist (Ki values >1700 nM, >2980 nM, and 1.1 nM for RARα, RARβ, and RARγ, respectively) for the treatment of osteoarthritis joint pain.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC42748 | AGN 193109 (sodium salt) | 2319838-82-7 | - | ||
A pan-RAR antagonist | |||||
| GC17730 | CD 3254 | 196961-43-0 | ROR/RAR/RXR | ||
A selective RXR agonist | |||||
| GC13199 | UVI 3003 | 847239-17-2 | Autophagy | ||
A pan-RXR antagonist | |||||
| GC66433 | Ro 41-5253 | 144092-31-9 | ROR/RAR/RXR | ||
Ro 41-5253 是一种具有口服活性的选择性维甲酸受体 RARα 拮抗剂。Ro 41-5253 可以与 RARα 结合而不诱导转录或影响 RAR/RXR 异二聚化和 DNA 结合。Ro 415253 可抑制癌细胞增殖并诱导细胞凋亡 (apoptosis)，具有抗肿瘤活性。 | |||||
| GB40268 | LY 2955303 dihydrochloride | 2469014-43-3 | - | ||
Potent and selective retinoic acid receptor gamma (RARγ) antagonist (Ki values >1700 nM, >2980 nM, and 1.1 nM for RARα, RARβ, and RARγ, respectively) for the treatment of osteoarthritis joint pain. | |||||
| GC18482 | all-trans-5,6-epoxy Retinoic Acid | 13100-69-1 | Cancer Biology | ||
An agonist of RAR isoforms | |||||
| GC15648 | BMS 493 | 215030-90-3 | ROR/RAR/RXR | ||
A pan-RAR inverse agonist | |||||